We are looking for a PhD student to join the team in the International Centre for Cancer Vaccine Science (ICCVS) hosted by the University of Gdańsk. The scholarship is offered in the frame of the project "The impact of UPF1 ATP mimetics on the mutant immunopeptidome”. The project is funded by the National Science Centre within the programme OPUS under grant agreement no. UMO-2020/39/B/NZ7/02677.
Key responsibilities include:
- Design and develop in silico screening pipelines to identify novel hits against the UPF1 helicase.
- Participate in biological evaluation for the selected ligands and their derivatives against the target; hUPF1.
- Ready to learn and design in vitro and in vivo experiments. Make in vitro experiments for the selected ligands (and derivatives) for the UPF1 protein using thermal shift assay and cellular thermal shift assay methods.
- Involve in making experiments for the FRET assay to study interactions between UPF1, UPF2, UPF3a, and UPF3b proteins.
- Preparing scientific publications and analysis of data from biological experiments.
Application deadline: 20 July 2025, 23:59:59
Detailed information in the attachment
Data publikacji
2025-06-25
